Lately I've been making a lot of single blocks (30's Jane, 365 Challenge, Splendid Sampler) rather than entire quilts. Things around the sewing machine can get chaotic really quickly.
My solution for this is to straighten up after each block. To make it quicker, I have a trash can right next to me for thread and fabric cut-offs as I go.
And this handy little Poppin tray to corral all the tools at the end.